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"Label-Free Interoperative Imaging based on Fiberoptic Coherent Raman Scattering techniques"

Stephen Wong
The Methodist Hospital Research Institute
Houston TX


The prevalent approach of in vivo molecular imaging is based on the injection of exogenous contrast agents or labels into human body to aid the tumor detection and diagnosis. However, the development of such diagnostic agents is treated similar to the development of drugs by FDA and thus subjects to the lengthy and expensive process of FDA approval, yet contrast agents have much smaller market as drugs. In this talk, we present an alternate paradigm of in vivo molecular imaging based on label-free molecular vibrational imaging, in particular, coherent anti-Stokes Raman scattering (CARS), to sidestep the problem. We will provide applications examples such as image-guided lung cancer diagnosis, nerve pairing prostatectomy, tumor margin detection during lumpectomy to illustrate the practicality and utility of the new label-free devices.

Tuesday, February 21, 2012
IQSE 578, 12:30 p.m.
Mitchell Physics Building

Institute for Quantum Science and Engineering
Texas A&M University

(brown bag lunch)