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"Spatial Offset Scattering Spectroscopy of Bone for Diagnosis of the Osteoporosis"

Ziyun Di
Department of Physics, Texas A&M University


Osteoporosis is a disease that affects more than 10 million people in the United States, with costs over 13.5 billion dollars every year. It is reported that by the year of 2020 half of all Americans older than 50 years will be at risk of an osteoporotic fragility fracture. Osteoporosis is characterized by low bone mass and structural deterioration of bone, leading to bone fragility and an increased tendency to fracture which depends on its micro-geometry (size, shape, and connectivity), the activities of the cells in the tissue, and the chemical properties of the tissue. The commonly used procedure for assessing the risk of osteoporotic fracture is via bone mineral density (BMD) assessment using dual-energy X-ray absorptiometry (DXA). Here, linear and Raman scattering are demonstrated in cortical bone and cancellous bone using a microscopic spatial offset detection. This technique may enable the diagnosis of early tissue alterations.

Tuesday, November 27, 2012
IQSE 578, 12:30 noon
Mitchell Physics Building

Institute for Quantum Science and Engineering
Texas A&M University

(Sandwiches and soda to be served at 12:00 noon)

Host: Marlan Scully